COMPARATIVE CHARACTERISTICS OF HISTOMORPHOLOGIC CHANGES IN THE TESTIS OF RATS EXPOSED TO INTERNAL AND EXTERNAL RADIATION

It is known that persons exposed to tonizing radiatton side by side with a different of damaging effects, in particular attention to given the reproductive system. The dominant role of neutron-activated radionuclide Manganese-56 (⁵⁶Mn) was noted in the treatises of Japanese scientists who studied the A-Bomb effects of Japanese cities deserving the interest nowaday. In this regard, the research purpose was to study the microscopic changes in the testes of rats exposed to B- and Y-radiatton. In experiment, male sex «Wistar» rats in amount of 30, weighting approximately 227-335 g. Necropsy of the animals were on the 3^rd, 14^th and 60^th days afer irradiatton, then the testes removed, afterward that was fixed in 10% formalin. Tissues fragments embedded in paraffin, then sections are manufactured serial transverse 4 mm thickness which were subsequently stained by hematoxylin and eosin (H&B). The finding of an experimental study demonstrated that neutron-activated manganese dioxide (⁵⁶Mn) effect the rates testis revealed a high risk level of internal radiation compared with the external radiation (⁶⁰Co) effects, that is confirmed by the presence of dystrophic and necrobiotic processes in late period. The data obtained confirm the role of ionizing radiation in the formation of histomorphological features depending on both dose and type of radiation.

ionizing radiation, testes, histomorphology, dystrophy, rats

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